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KMID : 0043320080310121525
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Archives of Pharmacal Research
2008 Volume.31 No. 12 p.1525 ~ p.1529
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Bioactivities of Polyphenolics from the Roots of Bauhinia racemosa
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Jain Renuka
Jain Satish C.
Rathore Kiran
Saxena Umesh
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Abstract
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Various extracts of Bauhinia racemosa Lamk. (roots) and the isolated polyphenolics, viz. 1,7,8,12b-tetrahydro-2,2,4-trimethyl-10-methoxy-2H-benzo [6,7] cyclohepta[1,2,3-de][1]benzopyran-5,9-diol (racemosol) (1), 1,7,8,12b-tetrahydro-2,2,4-trimethyl-2H-benzo[6,7]cyclohepta[1,2,3-de][1]benzopyran- 5,10,11-triol (2), and 1,7,8,12b-tetrahydro-2,2,4-trimethyl-2H-benzo[6,7] cyclohepta [1,2,3-de][1]benzopyran- 5,9,10-triol (de-O-methyl racemosol) (3) were screened for antibacterial, antifungal, and antiviral activities. The isolated compounds exhibited profound antibacterial and antifungal activities while methanol extract exhibited potential efficacy against Herpes simplex virus.
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KEYWORD
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Bauhinia racemosa Lamk., Polyphenolics, Bioactivities, Antibacterial, Antifungal, Antiviral
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